产品货号：
Z14437
中文名称：
ECSIT抗体
英文名称：
Anti-ECSIT Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ECSIT Antibody |
| 指标别名 | ECSIT;Evolutionarily conserved signaling intermediate in Toll pathway;mitochondrial;Protein SITPEC |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | ECSIT |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ECSIT recombinant protein (Position:E83-S339). |
| 实际分子量 | 49KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Evolutionarily conserved signaling intermediate in Toll pathway,mitochondrial (ECSIT),also known as SITPEC,is a protein that in humans is encoded by the ECSIT gene.Activation of NF-kB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses.Signals from these receptors are relayed by a number of adapter molecules such as TRIF,TIRAP,and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6.ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway.Recently however,ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis,indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways. |
| Uniprot ID | Q9BQ95 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ECSIT signaling integrator |
| 蛋白名全称 | Evolutionarily conserved signaling intermediate in Toll pathway,mitochondrial |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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